You’ll be headed through some wonderful brewery country there. If you’re traveling F-Su, you might consider Agrarian Ales, an absolutely wonderful farmhouse brewery that uses local ingredients and has a lovely outdoor dining area with a great view of their hop fields. They’re just off I-5 north of Eugene.
Another great choice is Corvallis’ Block 15, which is literally one of the best breweries in the world–and one of the best six or eight in Oregon. Great brewpub downtown and a nice taproom a bit out of town that might be more convenient.
Those are my two recommendations — they’re where I’d stop if I were in your car. Remember to have a designated driver!